Protoporphyrins Enhance Oligomerization and Enzymatic Activity of HtrA1 Serine Protease
نویسندگان
چکیده
منابع مشابه
Protoporphyrins Enhance Oligomerization and Enzymatic Activity of HtrA1 Serine Protease
High temperature requirement protein A1 (HtrA1), a secreted serine protease of the HtrA family, is associated with a multitude of human diseases. However, the exact functions of HtrA1 in these diseases remain poorly understood. We seek to unravel the mechanisms of HtrA1 by elucidating its interactions with chemical or biological modulators. To this end, we screened a small molecule library of 5...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2014
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0115362